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Milan to Palermo bus

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Milan - Palermo Bus Schedule

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Journey Information

There are 4 intercity buses per day from Milan to Palermo. Traveling by bus from Milan to Palermo usually takes around 22 hours and 19 minutes, but the fastest Autoservizi Salemi bus can make the trip in 21 hours,

Distance551 mi (887 km)
Shortest duration21h 0m
Cheapest price$16.08
Trips per day2
Most frequent serviceItabus
Bus lines2

Price trends for buses from Milan to Palermo

Monthly average prices

$150$120$90$60$30JJASONDJFMAM

What bus companies travel from Milan to Palermo?

There are two bus lines that have daily service from Milan to Palermo that you can compare and book on Wanderu. Of these two carriers, Itabus usually offers more choice, with 3 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
Autoservizi Salemi221h 23m$86.15
Itabus323h 20m$57.14
  • Autoservizi Salemi is an Italian bus company that travels the length of the Italian peninsula daily. Some notable routes include stops in Milan, Florence, Bologna, Marsala, and Palermo. Their modern buses have excellent amenities including air conditioning, power outlets, restrooms, WiFi, and snacks and drinks for sale.

  • Itabus is an Italian bus company servicing the whole peninsula, including major tourist hotspots like Rome, Trieste, and Catania. The company has both single and double-decker buses with clean, comfortable seats, complimentary WiFi, power outlets, restrooms, and air conditioning. Upgrade to a premium ticket for even larger seats and extendable armchairs.

Frequently Asked Questions

The bus takes an average of 22 hours and 19 minutes to cover the 551 miles from Milan to Palermo. However, the fastest bus only takes 21 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Palermo. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.

The first bus leaves at 8:00am and the last bus leaves at 10:00am. To see the times for all buses from Milan to Palermo, enter your specific travel dates in the search bar.

There are 4 scheduled buses that travel from Milan to Palermo every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

City Information

Milan

The fashion capital of the world, Milan, is a busy city brimming with activities and lavish nightlife. In spite of its frenetic modern lifestyle, Milan is also blessed with some amazing landmarks, of which the Milan Cathedral should be given special attention. Considered the largest and most unique Gothic structure in Italy, the cathedral took about 600 years to build, and its impressive gothic details will amaze all fans of architecture. The roof of the cathedral itself is accessible, so visitors can climb up to marvel at the city’s skyline and see the cathedral’s details up close. Another spot to consider is the Santa Maria delle Grazie, which currently houses “The Last Supper,” a masterpiece by the legendary artist Leonardo da Vinci. For those who enjoy old books, the Ambrosiana Library & Picture Gallery houses a vast collection of artworks, as well as rare ancient manuscripts.

For a taste of the unique Milanese cuisine, you could consider the Gente di Mare in Darsena, which offers superb seafood. If you wish to enjoy great local pizzas, Pizzium - Via Vigevano offers great dishes.

Milano Centrale is the city’s main train station, offering access to international destinations such as Berlin, Frankfurt and Munich. The main bus station in Milan is Lampugnano, serving as the local hub for bus carriers like FlixBus, BlaBlaCar Bus and Union Ivkoni. The main airport in Milan is Malpensa Airport located about 32 miles northwest of the city center.

Station Information

Where does the bus leave from in Milan?

Main departure station: Lampugnano

Buses to Palermo leave from 3 stations in Milan.

All bus stations in Milan:

  • Lampugnano

  • Milan (San Donato M3)

  • San Donato Bus Station

Where does the bus arrive in Palermo?

Main arrival station: Palermo Central Railway Station

These are the two stations where buses may stop when they arrive in Palermo.

All bus stations in Palermo:

  • Palermo Central Railway Station

  • Via Tommaso Fazello - Autostazione

Get around town with Moovit

Find the best way to get to and from any station in Palermo by public transit, courtesy of Moovit. Search now

Need a return trip from Palermo to Milan?

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